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<p>When examined in the usual way with microscope oil alleged cryoglobulins appear as striations with a blue cast.</p>
<p>Serum of a patient at the time of hospitalisation (left) and 12 hours later (right): The serum is coloured red-brown due to intravascular haemolysis.</p>
<p>Bone marrow analysis of a patient revealing breast cancer metastases. </p>
<p>Bone marrow cytology (May-Grünwald-Giemsa stain) of a 37-year old patient with aplastic anaemia, showing a reduced cell content: In the upper half of the picture only fat cells are present, in the lower third haematopoietic cells are still present.</p>
<p>Bone marrow cytology (May-Grünwald-Giemsa stain) of a patient with CML demonstrating an extremely elevated number of cells: Granulopoiesis is enhanced, megakaryocyte count is increased. Cytogenetic detection of the Philadelphia chromosome (Ph1) confirmed the diagnosis of CML.</p>
<p>This bone marrow cytology (May-Grünwald-Giemsa stain) of a 75-year old patient with chronic myelomonocytic leukaemia (CMML) shows in addition a multiple myeloma with plenty of plasma cells (->).</p>
<p>Bone marrow cytology (May-Grünwald-Giemsa stain) of a patient with immunocytoma showing a dense infiltration of small lymphocytes (L), lymphoplasmacytic cells (LP), a few plasma cells (P) and mast cells (M). The cells produce monoclonal IgM, characterising it as a Waldenström's disease. </p>
<p>Bone marrow cytology (May-Grünwald-Giemsa stain) of a patient with multiple myeloma showing atypical plasma cells.</p>
<p>Bone marrow cytology (May-Grünwald-Giemsa stain) of an 82-year old patient, in which, considering the age of this patient, a substantial increase of cells and dysplastic changes in all cell lineages are evident. The percentage of blasts is below 5%. This is a refractory cytopenia with multilineage dysplasia (RCMD).</p>